This work describes the development of a compact instrument as a generic measurement platform for the determination of bionanalytes using sensors and biosensors. This has been achieved with the inclusion, in an unique instrument, the photodiode, the potentiostat and the dynamically reconfigurable electronics that adapts the analog processing to the electrochemiluminescent (ECL) signal. Main advantages of our design lie on portability and low cost because of the use of a photodiode instead of a costly or bulky photomultiplier; versatility due to its totally reconfigurable analog conditioning (gain, filtering, noise reduction) with a Field Programmable Analog Array (FPAA); and the use of a few microliters of sample volume. The use of reconfigurable analog devices as sensor signal conditioning permit us to probe different analog processing in real time, changing the configuration of the analog circuit in few seconds. Therefore, we think that reconfigurable circuit for analog conditioning is very suitable for this type of instrumentation prototyping.